Waters recommends you filter buffers and samples using a 0.2µm filter prior to analysis. Filtration protects the column and instrument components from a build-up of particulate matter, improving column lifetime and minimizing system downtime. The ACQUITY Column In-line filter kit comes complete with the holder and five 0.2µm stainless steel replacement filters. You can order a package of five replacement filters using Part Number 700002775 which will work with the in-line filter kit. The ACQUITY Column In-line filters are designed to work with Waters stainless steel columns that are packed with smaller particles; ACQUITY Column In-line filters are not designed to work with PREMIER columns.